MIG1 AS A POSITIVE REGULATOR FOR THE HISTIDINE BIOSYNTHESIS PATHWAY AND AS A GLOBAL REGULATOR IN THERMOTOLERANT YEAST KLUYVEROMYCES MARXIANUS

MIG1 as a positive regulator for the histidine biosynthesis pathway and as a global regulator in thermotolerant yeast Kluyveromyces marxianus

Abstract Kmmig1 as a disrupted mutant of MIG1 encoding a regulator for End Cap Beam glucose repression in Kluyveromyces marxianus exhibits a histidine-auxotrophic phenotype.Genome-wide expression analysis revealed that only HIS4 in seven HIS genes for histidine biosynthesis was down-regulated in Kmmig1.Consistently, introduction of HIS4 into Kmmig1

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German Foreign Policy in the Face of Current Challenges

The article analyzes the features of German foreign policy on the eve of the September (2021) elections to the Bundestag and the gradual overcoming of the crisis consequences of the coronavirus pandemic.The priorities of the foreign policy based on the value approach remain the European and transatlantic vectors, as well as relations with the main

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Beneficial effects of a Q-ter based nutritional mixture on functional performance, mitochondrial function, and oxidative stress in rats.

Mitochondrial dysfunction and oxidative stress are central mechanisms underlying the aging process and the pathogenesis of many age-related diseases.Selected antioxidants and specific combinations of nutritional compounds could target many biochemical pathways that affect both oxidative stress and mitochondrial function and, thereby, preserve or en

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